Author Topic: Spagbook  (Read 447172 times)

Salty

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Re: Spagbook
« Reply #6990 on: March 23, 2017, 06:19:17 pm »
Hey new Spag! Welcome.

The world is a car and you're the crash test dummy.

Junkenstein

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Re: Spagbook
« Reply #6991 on: March 23, 2017, 07:12:43 pm »
Don't be cephalopobic.

3 Points.

You're currently joint 4th on points for your reference.
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the Tart

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Re: Spagbook
« Reply #6992 on: March 24, 2017, 08:14:46 pm »
Hey new Spag! Welcome.



Well, thank you. I'd love to stay and play but as you can see I'm hard at work.

Mesozoic Mister Nigel

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Re: Spagbook
« Reply #6993 on: March 24, 2017, 09:04:53 pm »
Hey new Spag! Welcome.



Well, thank you. I'd love to stay and play but as you can see I'm hard at work.

So we've  got Salty and Tart here. We just need sweet, bitter, and glutamate.
“I’m guessing it was January 2007, a meeting in Bethesda, we got a bag of bees and just started smashing them on the desk,” Charles Wick said. “It was very complicated.”


The Wizard Joseph

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Re: Spagbook
« Reply #6994 on: March 24, 2017, 09:45:51 pm »
Hey new Spag! Welcome.



Well, thank you. I'd love to stay and play but as you can see I'm hard at work.

So we've  got Salty and Tart here. We just need sweet, bitter, and glutamate.

I just had to go and Google "the sixth flavor" initially vaguely thinking I could make a Prince joke based on your avatar Nigel...

Then I found several articles about "oleogustus" apparently also known as "awful". The taste of oxidized fat.

http://www.eater.com/2015/8/3/9090099/scientists-fat-sixth-taste

And this led me to "Emperor Fatberg Oleogustus, the Awful" as a character concept and then I hit "post" before it gets any worse.
You can't get out backward.  You have to go forward to go back.. better press on! - Willie Wonka, PBUH

Life can be seen as a game with no reset button, no extra lives, and if the power goes out there is no restarting.  If that's all you see life as you are not long for this world, and never will get it.

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Vanadium Gryllz

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Re: Spagbook
« Reply #6995 on: March 25, 2017, 09:43:00 am »
(snip)

And this led me to "Emperor Fatberg Oleogustus, the Awful" as a character concept and then I hit "post" before it gets any worse.

 :lulz:
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Mesozoic Mister Nigel

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Re: Spagbook
« Reply #6996 on: March 26, 2017, 02:18:27 am »
Hey new Spag! Welcome.


Well, thank you. I'd love to stay and play but as you can see I'm hard at work.

So we've  got Salty and Tart here. We just need sweet, bitter, and glutamate.

I just had to go and Google "the sixth flavor" initially vaguely thinking I could make a Prince joke based on your avatar Nigel...

Then I found several articles about "oleogustus" apparently also known as "awful". The taste of oxidized fat.

http://www.eater.com/2015/8/3/9090099/scientists-fat-sixth-taste

And this led me to "Emperor Fatberg Oleogustus, the Awful" as a character concept and then I hit "post" before it gets any worse.

I'll buy it when they identify a receptor for it.
“I’m guessing it was January 2007, a meeting in Bethesda, we got a bag of bees and just started smashing them on the desk,” Charles Wick said. “It was very complicated.”


The Wizard Joseph

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Re: Spagbook
« Reply #6997 on: March 26, 2017, 02:42:54 am »
Hey new Spag! Welcome.


Well, thank you. I'd love to stay and play but as you can see I'm hard at work.

So we've  got Salty and Tart here. We just need sweet, bitter, and glutamate.

I just had to go and Google "the sixth flavor" initially vaguely thinking I could make a Prince joke based on your avatar Nigel...

Then I found several articles about "oleogustus" apparently also known as "awful". The taste of oxidized fat.

http://www.eater.com/2015/8/3/9090099/scientists-fat-sixth-taste

And this led me to "Emperor Fatberg Oleogustus, the Awful" as a character concept and then I hit "post" before it gets any worse.

I'll buy it when they identify a receptor for it.

If I have understood that first part of this correctly there are receptors.

https://academic.oup.com/chemse/article/40/7/507/400784/Oleogustus-The-Unique-Taste-of-Fat

most of the technical stuff and experimental description is beyond me, but it would seem that most of the qualifications are in order. I totally wouldn't have thought to look into it if you hadn't said something and had to get pretty specific with the search thread to eventually find this.
You can't get out backward.  You have to go forward to go back.. better press on! - Willie Wonka, PBUH

Life can be seen as a game with no reset button, no extra lives, and if the power goes out there is no restarting.  If that's all you see life as you are not long for this world, and never will get it.

"Ayn Rand never swung a hammer in her life and had serious dominance issues" - The Fountainhead

"World domination is such an ugly phrase. I prefer to call it world optimisation."
 - Harry Potter and the Methods of Rationality :lulz:

Mesozoic Mister Nigel

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Re: Spagbook
« Reply #6998 on: March 26, 2017, 08:59:37 pm »
Hey new Spag! Welcome.


Well, thank you. I'd love to stay and play but as you can see I'm hard at work.

So we've  got Salty and Tart here. We just need sweet, bitter, and glutamate.

I just had to go and Google "the sixth flavor" initially vaguely thinking I could make a Prince joke based on your avatar Nigel...

Then I found several articles about "oleogustus" apparently also known as "awful". The taste of oxidized fat.

http://www.eater.com/2015/8/3/9090099/scientists-fat-sixth-taste

And this led me to "Emperor Fatberg Oleogustus, the Awful" as a character concept and then I hit "post" before it gets any worse.

I'll buy it when they identify a receptor for it.

If I have understood that first part of this correctly there are receptors.

https://academic.oup.com/chemse/article/40/7/507/400784/Oleogustus-The-Unique-Taste-of-Fat

most of the technical stuff and experimental description is beyond me, but it would seem that most of the qualifications are in order. I totally wouldn't have thought to look into it if you hadn't said something and had to get pretty specific with the search thread to eventually find this.

Nope. I looked at the studies they cite and they offer some limited support for the possibility of fat-specific taste receptors in rats.
“I’m guessing it was January 2007, a meeting in Bethesda, we got a bag of bees and just started smashing them on the desk,” Charles Wick said. “It was very complicated.”


Mesozoic Mister Nigel

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Re: Spagbook
« Reply #6999 on: March 26, 2017, 09:05:18 pm »
The cellular mechanisms that transduce environmental stimuli into relevant neuronal signaling pathways are my specific subfield in neurobiology, and what I do is test proposed signaling pathways to find out whether the proposition holds water, so my first question is always "show me the pathway". There certainly could be primary taste receptors for unpleasant fatty acids in humans, I am just not comfortable accepting the specific claim without evidence that is a little better than circumstantial.
“I’m guessing it was January 2007, a meeting in Bethesda, we got a bag of bees and just started smashing them on the desk,” Charles Wick said. “It was very complicated.”


Junkenstein

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Re: Spagbook
« Reply #7000 on: March 26, 2017, 09:47:35 pm »
My heritage forces me to take umbrage at the concept of oxidized fat being classed as "awful". Culinary heathens the lot of you.
Nine naked Men just walking down the road will cause a heap of trouble for all concerned.

The Wizard Joseph

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Re: Spagbook
« Reply #7001 on: March 27, 2017, 12:15:52 am »
The cellular mechanisms that transduce environmental stimuli into relevant neuronal signaling pathways are my specific subfield in neurobiology, and what I do is test proposed signaling pathways to find out whether the proposition holds water, so my first question is always "show me the pathway". There certainly could be primary taste receptors for unpleasant fatty acids in humans, I am just not comfortable accepting the specific claim without evidence that is a little better than circumstantial.

 :lol: And so my IF once again proves a "nope, sorry newb", ah well.

My heritage forces me to take umbrage at the concept of oxidized fat being classed as "awful". Culinary heathens the lot of you.

So... a pint of used fryer grease that's sat long enough to get rank is... culinary orthodoxy to you??
You can't get out backward.  You have to go forward to go back.. better press on! - Willie Wonka, PBUH

Life can be seen as a game with no reset button, no extra lives, and if the power goes out there is no restarting.  If that's all you see life as you are not long for this world, and never will get it.

"Ayn Rand never swung a hammer in her life and had serious dominance issues" - The Fountainhead

"World domination is such an ugly phrase. I prefer to call it world optimisation."
 - Harry Potter and the Methods of Rationality :lulz:

Mesozoic Mister Nigel

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Re: Spagbook
« Reply #7002 on: March 27, 2017, 02:41:20 am »
My heritage forces me to take umbrage at the concept of oxidized fat being classed as "awful". Culinary heathens the lot of you.

Dear god, please tell me that you people don't eat rancid grease. That shit is FULL of ROS.
“I’m guessing it was January 2007, a meeting in Bethesda, we got a bag of bees and just started smashing them on the desk,” Charles Wick said. “It was very complicated.”


Junkenstein

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Re: Spagbook
« Reply #7003 on: March 27, 2017, 12:33:42 pm »
I'm pretty sure that I could give you a mild cardiac event just by telling you what I ate the last time I went home.
Nine naked Men just walking down the road will cause a heap of trouble for all concerned.

Mesozoic Mister Nigel

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Re: Spagbook
« Reply #7004 on: March 27, 2017, 03:09:19 pm »
Savages.
“I’m guessing it was January 2007, a meeting in Bethesda, we got a bag of bees and just started smashing them on the desk,” Charles Wick said. “It was very complicated.”