Anyone taken a look at Pokemon Tabletop Adventures? Mechanically it's a lot like 4e in that moves work just like Powers (at-will... daily...etc) and it follows a more Gamist tone. I don't particularly like 4e for that reason, but I think that in P:TA it works quite well since, Pokemon is, well, a video game. The classes include a holy avatar of legendary Pokemon that can worship Missingno and get item-duplicating abilities. Each time he uses them, he risks being glitched out of reality forever, treated like he never even existed. If that isn't enough to pique your interest, I don't know what is.
I've considered it, but my gaming group has been in shambles since I started college. I need to get a steady group together before I really want to try anything weird out. Plus, I normally play the pulpy, half-comedic adventures and run the horror games, and I'm not sure of anyone but me who would run PTA.