Satirical comedy. It starts in a factory in the flyover states, where a redneck woman is talking to a coworker. She launches into an anti-immigration tirade, "they're living off the government, they're bringing drugs, they're taking our jobs". The friend replies that they don't believe that. The redneck woman then launches into a convoluted story about how immigrants pushed her out of her previous career as a drug dealing welfare queen. This flashback forms the bulk of the movie.
(like, I can't be the only person who's noticed that those arguments, taken together, imply that the speaker's ideal preferred job is drug dealer)