I've read about this shit for years but wait for the video sequences around 12:30. Actually seeing a visualisation of what's going on during replication and factory biological production is fucking stunning. RNA is no longer a squiggly diagram in a book!
http://www.youtube.com/watch?v=It83JKAxejM (http://www.youtube.com/watch?v=It83JKAxejM)
Quote from: P3nT4gR4m on March 13, 2014, 11:00:09 PM
I've read about this shit for years but wait for the video sequences around 12:30. Actually seeing a visualisation of what's going on during replication and factory biological production is fucking stunning. RNA is no longer a squiggly diagram in a book!
http://www.youtube.com/watch?v=It83JKAxejM (http://www.youtube.com/watch?v=It83JKAxejM)
I'm starting to get scared simply because I'm happy with how awesome the fucking stuff we have now is. Even just a smart phone really
That is amaze-balls. Did you guys get the zipper analogy in high school bio? Something unzips the DNA and then it's zipped up into two other zippers? This video clears that shit all up.
I realised when I was watching this that I had learned a lot of it in high school but something about seeing it simulated like that was kind of like the effect when a book you've read is turned into a movie. Like making it concrete in my head.
Great link, thanks!
Watched a chunk on my lunch break. When I get a chance to finish it, and think a bit, I may have things to say. Neat graphic for the DNA replication.
Sat and watched the video through. What blows my mind is the essential logistics to the whole cellular function. A cell is like a dense megacity full of monotask worker drones and multi function fabricators. All of it works in perfect sync and the system adapts to changing circumstances on the fly. It takes no breaks and runs flat out at incredible speed until it crashes and other systems scoop up the pieces. All without a boss or work instructions other than what is already pre programmed in the DNA.
We just can't achieve anything equivalent to it on our scale. Imagine if your ribosomes got uppity, unionized, and started to call in sick when tired of your shit. But they don't. They're not conscious. They're just ribosomes. Thank God.
Cellular function is amazing. But don't forget that they don't just do what's programmed in the DNA in a straightforward linear way, they also do alternate functions that are turned on or off according to complex interactions with the environment that we don't really understand.
http://aeon.co/magazine/nature-and-cosmos/an-expert-roundtable-on-the-selfish-gene-and-evolution/
What Nigel said.
Also, in a very real way the complex interactions in the environment are also carriers for evolutionary relevant data.
What really fucks my head is that, in one respect, what's happening is pretty straightforward - there's a machine that processes base4 ticker tape code. Program is massive (over 3 gigs in the case of humans) and that's machine-code not high level scripting but, essentially, I can just about wrap my head around it. The weird bit for me is the fact that the code creates the computer that executes it.
Self replication doesn't make sense. It's like you're saying "Here's a disk, just stick it in the machine it will make when you run it and then click "okay" to continue" There's some real sneaky shit at work here :eek: :argh!:
Quote from: P3nT4gR4m on March 20, 2014, 09:38:44 AM
What really fucks my head is that, in one respect, what's happening is pretty straightforward - there's a machine that processes base4 ticker tape code. Program is massive (over 3 gigs in the case of humans) and that's machine-code not high level scripting but, essentially, I can just about wrap my head around it. The weird bit for me is the fact that the code creates the computer that executes it.
Self replication doesn't make sense. It's like you're saying "Here's a disk, just stick it in the machine it will make when you run it and then click "okay" to continue" There's some real sneaky shit at work here :eek: :argh!:
It's all in the bootstrapping.
This computer was booted 4.5 billion years ago and rebooting is impossible.
Quote from: :regret: on March 20, 2014, 11:14:05 AM
Quote from: P3nT4gR4m on March 20, 2014, 09:38:44 AM
What really fucks my head is that, in one respect, what's happening is pretty straightforward - there's a machine that processes base4 ticker tape code. Program is massive (over 3 gigs in the case of humans) and that's machine-code not high level scripting but, essentially, I can just about wrap my head around it. The weird bit for me is the fact that the code creates the computer that executes it.
Self replication doesn't make sense. It's like you're saying "Here's a disk, just stick it in the machine it will make when you run it and then click "okay" to continue" There's some real sneaky shit at work here :eek: :argh!:
It's all in the bootstrapping.
This computer was booted 4.5 billion years ago and rebooting is impossible.
Correction: Rebooting was impossible. Venter Institute have cracked that one. Natural selection is being phased out as we speak.
Quote from: P3nT4gR4m on March 20, 2014, 04:30:20 PM
Quote from: :regret: on March 20, 2014, 11:14:05 AM
Quote from: P3nT4gR4m on March 20, 2014, 09:38:44 AM
What really fucks my head is that, in one respect, what's happening is pretty straightforward - there's a machine that processes base4 ticker tape code. Program is massive (over 3 gigs in the case of humans) and that's machine-code not high level scripting but, essentially, I can just about wrap my head around it. The weird bit for me is the fact that the code creates the computer that executes it.
Self replication doesn't make sense. It's like you're saying "Here's a disk, just stick it in the machine it will make when you run it and then click "okay" to continue" There's some real sneaky shit at work here :eek: :argh!:
It's all in the bootstrapping.
This computer was booted 4.5 billion years ago and rebooting is impossible.
Correction: Rebooting was impossible. Venter Institute have cracked that one. Natural selection is being phased out as we speak.
Link?
Anyway, rebooting life would leave you with a completely different computer. That is not rebooting, that is more like formatting or extreme clean booting.
https://www.youtube.com/watch?v=QHIocNOHd7A (https://www.youtube.com/watch?v=QHIocNOHd7A)
Not rebooting life itself. Synthesising it. A starting point for a new phase of evolution by intelligent design. Natural selection is over. We are driving it from this point forward.
The way I see it, right now, evolution is still crawling onward at evolution speed, whilst we get up to speed with the Dev Kit documentation. This might take decades, centuries or maybe even millennia (yeah, right) but I'm confident we'll crack it a long time before nature creates a new creature. Even in the interim we're using life's nano-robotics to build stuff we want, and defeat natural efforts to do stuff we don't want. Selection is on our terms now.
Quote from: Nigel on March 20, 2014, 04:47:52 AM
Cellular function is amazing. But don't forget that they don't just do what's programmed in the DNA in a straightforward linear way, they also do alternate functions that are turned on or off according to complex interactions with the environment that we don't really understand.
http://aeon.co/magazine/nature-and-cosmos/an-expert-roundtable-on-the-selfish-gene-and-evolution/
Was picking through the articles in the link earlier and a thought struck me. The intro talk given in the OP stated that in many ways the body may be seen as much as an ecosystem as a lifeform in itself. Perhaps there is a guidance of sorts going on in the interplay of these internal species. Our own cells taking cues from the other cells in the structure, like in nature seeing birds take flight and knowing there is a predator about or perhaps relying on some byproduct of the other species for cues or optimal function. Kinda mindblowing to consider yourself an ecosystem more intricate than a rainforest, and humbling to consider how easily that might get jacked up by one's thoughtless actions.
Quote from: P3nT4gR4m on March 20, 2014, 09:28:22 PM
https://www.youtube.com/watch?v=QHIocNOHd7A (https://www.youtube.com/watch?v=QHIocNOHd7A)
Not rebooting life itself. Synthesising it. A starting point for a new phase of evolution by intelligent design. Natural selection is over. We are driving it from this point forward.
The way I see it, right now, evolution is still crawling onward at evolution speed, whilst we get up to speed with the Dev Kit documentation. This might take decades, centuries or maybe even millennia (yeah, right) but I'm confident we'll crack it a long time before nature creates a new creature. Even in the interim we're using life's nano-robotics to build stuff we want, and defeat natural efforts to do stuff we don't want. Selection is on our terms now.
This could be the coolest way to doom us all. Patented, copyrighted, synthetic lifeforms. That may take offence at their servitude one day. Gosh where have I heard a story like that before?
Quote from: a somewhat wiser Joe. on March 25, 2014, 08:40:52 PM
Quote from: P3nT4gR4m on March 20, 2014, 09:28:22 PM
https://www.youtube.com/watch?v=QHIocNOHd7A (https://www.youtube.com/watch?v=QHIocNOHd7A)
Not rebooting life itself. Synthesising it. A starting point for a new phase of evolution by intelligent design. Natural selection is over. We are driving it from this point forward.
The way I see it, right now, evolution is still crawling onward at evolution speed, whilst we get up to speed with the Dev Kit documentation. This might take decades, centuries or maybe even millennia (yeah, right) but I'm confident we'll crack it a long time before nature creates a new creature. Even in the interim we're using life's nano-robotics to build stuff we want, and defeat natural efforts to do stuff we don't want. Selection is on our terms now.
This could be the coolest way to doom us all. Patented, copyrighted, synthetic lifeforms. That may take offence at their servitude one day. Gosh where have I heard a story like that before?
History suggests it will doom us all but it'll save us all from the same doom and bring a bunch of cool new shit in it's wake.
Quote from: P3nT4gR4m on March 25, 2014, 09:25:21 PM
Quote from: a somewhat wiser Joe. on March 25, 2014, 08:40:52 PM
Quote from: P3nT4gR4m on March 20, 2014, 09:28:22 PM
https://www.youtube.com/watch?v=QHIocNOHd7A (https://www.youtube.com/watch?v=QHIocNOHd7A)
Not rebooting life itself. Synthesising it. A starting point for a new phase of evolution by intelligent design. Natural selection is over. We are driving it from this point forward.
The way I see it, right now, evolution is still crawling onward at evolution speed, whilst we get up to speed with the Dev Kit documentation. This might take decades, centuries or maybe even millennia (yeah, right) but I'm confident we'll crack it a long time before nature creates a new creature. Even in the interim we're using life's nano-robotics to build stuff we want, and defeat natural efforts to do stuff we don't want. Selection is on our terms now.
This could be the coolest way to doom us all. Patented, copyrighted, synthetic lifeforms. That may take offence at their servitude one day. Gosh where have I heard a story like that before?
History suggests it will doom us all but it'll save us all from the same doom and bring a bunch of cool new shit in it's wake.
Hm. I agree. Hell just 'cuz you be doomed ain't no reason to stop having fun. The cool new shit is gonna be major league too. I want to be able to enjoy it. We could be, as you neatly stated in another thread, about to crack the machine code and start scripting biology systems. To me even the worst that could come of this is an acceptable risk for the chance to see the possible benefits. Either or both may be seen in my own lifetime.
That I got to be a being in such an incredible time gives me a hollow shivery :horrormirth:. I mean I deserve none of it, yet here I am living in the midst of the greatest change in history so far. :eek: Now what? Guess we shall see eh?
Quote from: P3nT4gR4m on March 20, 2014, 09:28:22 PM
A starting point for a new phase of evolution by intelligent design.
We can't even make cars that work properly.
This is gonna be HILARIOUS!
Quote from: The Good Reverend Roger on March 25, 2014, 11:48:44 PM
Quote from: P3nT4gR4m on March 20, 2014, 09:28:22 PM
A starting point for a new phase of evolution by intelligent design.
We can't even make cars that work properly.
This is gonna be HILARIOUS!
Yes we can, there's just more money in making cars that break down often. In addition new parts are constantly added to existing perfectly fine cars giving them new ways to break or be hacked.