Hehehehe Squarepusher is a bit too irregular to run to for my tastes (apart from that he's awesome, btw).
Anyway, I just speeded up one of my running mixes from 145BPM to 160BPM for a tryout... Well it's certainly interesting

[the music itself turned out fine, btw, I used a combo of +6% tempo and +4% speed, together making 160BPM, while changing the pitch only 4% and still retaining a decent sound quality]
Having tried that, now I don't believe for a second that any normal person could actually run to 180BPM. Maybe they were talking about the 100m Olympic sprinters or something.
Anyway, turns out that 160 is ever so slightly too fast for me. I noticed I wasn't able to keep up with all the steps, skipping. You notice because suddenly the snare-drum is at your left foot while it was at your right a minute ago

So next time I'll just load a 150 and 155 BPM version to my mp3 player, see what works best.
And who knows, in a week or two I might be able to keep up with the 160 one as well. I just don't think I'd ever be able to do 180 without having some professional coach telling me exactly how to move my legs and such.