Maybe I'm a little biased, since I enjoy getting pierced so much. Keep that in mind.
I feel that pain and hardship breed strength. Pain is, for one thing, integral to the true understanding of pleasure, imo. You cant truly grasp pleasure and happiness without pain and unhappiness.
Its like this; by denying pain, by completely ridding ourselves of it, we would be cutting ourselves off from a fundamental part of the human experience. From my understanding, H+ is about transcending the human condition, but I dont think you can do that by subtracting. Rather, the goal should be addition. Pain is a part of who and what we are, and by ridding ourselves of it I think we would be lessening ourselves. Now, changing pain would be one thing, learning to control it so that it would still be useful, but not unbearable, that I could see as good, but removing our pain centers is as bad as removing our pleasure centers.
Through pain and pleasure we connect with our bodies. We communicate with our bodies. Also, I dont think there is any difference between the two. In the words of a very wise man; "There is no such thing as pain. There is only powerful sensation." I dont think it possible to alter our ability to feel sensation without altering our ability to feel ALL sensation.
Pain is important for physiological reasons. Suffering is psychological.
This, I think, is an important disctinction. The elimination (or lessening) of suffering could be desirable. But not pain.