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Pot/drugs: An all-encompassing explanation.

Started by Doktor Howl, February 15, 2010, 09:50:26 PM

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Telarus

I haven't studied biochemistry since H/S, but this is a very interesting site that give a visual explanation of the chemical actions of various drugs:

http://learn.genetics.utah.edu/content/addiction/drugs/mouse.html

QuoteNote:

The simplified mechanisms of drug action presented here are just a small part of the story. When drugs enter the body they elicit very complex effects in many different regions of the brain. Often they interact with many different types of neurotransmitters and may bind with a variety of receptor types in a variety of different locations. For example, THC in marijuana can bind with cannabinoid receptors located on the presynaptic and/or postsynaptic cell in a synapse.

Where applicable, this presentation primarily depicts how drugs interact with dopamine neurotransmitters because this website focuses on the brain's reward pathway. Mouse Party is designed to provide a small glimpse into the chemical interactions at the synaptic level that cause the drug user to feel 'high'.

Telarus, KSC,
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Bu🤠ns

Quote from: Telarus on February 22, 2010, 04:31:03 AM
I haven't studied biochemistry since H/S, but this is a very interesting site that give a visual explanation of the chemical actions of various drugs:

http://learn.genetics.utah.edu/content/addiction/drugs/mouse.html

QuoteNote:

The simplified mechanisms of drug action presented here are just a small part of the story. When drugs enter the body they elicit very complex effects in many different regions of the brain. Often they interact with many different types of neurotransmitters and may bind with a variety of receptor types in a variety of different locations. For example, THC in marijuana can bind with cannabinoid receptors located on the presynaptic and/or postsynaptic cell in a synapse.

Where applicable, this presentation primarily depicts how drugs interact with dopamine neurotransmitters because this website focuses on the brain's reward pathway. Mouse Party is designed to provide a small glimpse into the chemical interactions at the synaptic level that cause the drug user to feel 'high'.



That was pretty neat.

the last yatto

Quote from: Triple Zero on February 21, 2010, 07:08:54 PM
Except maybe through years of meditation practice and yoga or

... a really EPIC MOVIE
Look, asshole:  Your 'incomprehensible' act, your word-salad, your pinealism...It BORES ME.  I've been incomprehensible for so long, I TEACH IT TO MBA CANDIDATES.  So if you simply MUST talk about your pineal gland or happy children dancing in the wildflowers, go talk to Roger, because he digs that kind of shit

Bruno

Quote from: Pēleus on February 22, 2010, 06:11:04 AM
Quote from: Triple Zero on February 21, 2010, 07:08:54 PM
Except maybe through years of meditation practice and yoga or

... a really EPIC MOVIE

Robot .

Unicorn.

Attack.


I think I saw God, man.
Formerly something else...

nuclearcabbage

Quote from: Rev. What's-His-Name? on February 21, 2010, 08:41:26 PM
Quote from: nuclearcabbage on February 21, 2010, 08:37:03 PM
i am under the impression that "natural" things/events are pretty much anything and everything we can imagine...

how can anything be "unnatural"?

where does all this "unnatural" shit come from?

does it come from this completely "natural" universe?

Geez, it's pretty fucking obvious that the context of "natural" is being applied to what the human body is used to dealing with and what is isn't.  So, you can play your fancy pants pedantry game and call an iPod natural.  Now, try eating your iPod and see what happens.  Please let me know how that comes out.  

but...you know very well what'll come out...!
><><><><><><

Pope Pixie Pickle

My sister has had to stop giving Eris, the cat that used to be mine catnip as the comedowns make her violent.

Doktor Howl

Quote from: Rainy Day Pixie on February 22, 2010, 10:00:55 AM
My sister has had to stop giving Eris, the cat that used to be mine catnip as the comedowns make her violent.

When I was stuck with a cat, catnip only made it sneeze.
Molon Lube

AFK

Quote from: BabylonHoruv on February 21, 2010, 11:54:12 PM
You give your cats recreational drugs?  What would your employer say?

The person who decided to hire me is a Grade A dumbass who clearly has no good understanding of substance abuse prevention, so I could really care less what he thinks. 

I also had my cat fixed.  What would Gloria Allred think about that?
Cynicism is a blank check for failure.

AFK

Quote from: BabylonHoruv on February 22, 2010, 01:10:41 AM
I meant that in a lighthearted way.  I was also trying to use it to stretch the "drugs are bad, even for cats" theme that I saw RWHN introducing there.  (or at least the "drugs don't do anything aside from stimulate the pleasure center and get you fucked up" theme)  I wasn't trying to disrespect his work with the statement and hope he didn't take it that way.

If I hurt your feelings WHN or if you feel I was dismissing your job I apologize, I do think that what you do is valuable and I am glad there are people like you out there trying to keep children from getting involved with drug use, I am especcially glad that some of those people, like you, are open minded and intelligent and willing to engage in debate on the possibilities of merit in drugs or merit in legalization of drugs.

I also notice these threads have a tendency to die shortly after RWHN gets involved in them, because people do tend to attack his credibility or the position that he holds.  I know that has undoubtedly set people up to watch out for that sort of thing, but I think if we allow it to derail the discussion, especcially when it has not actually happened, as in this case, that we are going to repeat the same discussion over and over because it never actually reaches any sort of conclusion.

Well. if it helps.  A new work week is beginning which means I'll be disappearing back into the ether.  Please, carry on. 
Cynicism is a blank check for failure.

Doktor Howl

Quote from: Rev. What's-His-Name? on February 22, 2010, 10:50:16 AM
Quote from: BabylonHoruv on February 22, 2010, 01:10:41 AM
I meant that in a lighthearted way.  I was also trying to use it to stretch the "drugs are bad, even for cats" theme that I saw RWHN introducing there.  (or at least the "drugs don't do anything aside from stimulate the pleasure center and get you fucked up" theme)  I wasn't trying to disrespect his work with the statement and hope he didn't take it that way.

If I hurt your feelings WHN or if you feel I was dismissing your job I apologize, I do think that what you do is valuable and I am glad there are people like you out there trying to keep children from getting involved with drug use, I am especcially glad that some of those people, like you, are open minded and intelligent and willing to engage in debate on the possibilities of merit in drugs or merit in legalization of drugs.

I also notice these threads have a tendency to die shortly after RWHN gets involved in them, because people do tend to attack his credibility or the position that he holds.  I know that has undoubtedly set people up to watch out for that sort of thing, but I think if we allow it to derail the discussion, especcially when it has not actually happened, as in this case, that we are going to repeat the same discussion over and over because it never actually reaches any sort of conclusion.

Well. if it helps.  A new work week is beginning which means I'll be disappearing back into the ether.  Please, carry on. 

Jebus, RWHN, don't let BH get under your skin.  It's what he's after.
Molon Lube

AFK

Oh, I'm not.  Not at all.  And if I didn't have a firewall at work, I'd be prone to continuing the discussion. 
Cynicism is a blank check for failure.

Triple Zero

Quote from: Horrendous Foreign Love Stoat on February 22, 2010, 11:01:38 AM
on the subject of catnip, http://www.instructables.com/id/DIY-Kitty-Crack%3a--ultra-potent-catnip-extract/ turns catnip into an all powerful 'makes the cat steal and pawn the vcr for more sweet sweet goodness' extract

couple of drops on a toy rat and its 'instant favorite toy' time. I'd personally not apply this direct to the kitty mind you, but the creator says

QuoteThe upshot is that it's pretty safe. In the last of the references below, the LD50 of nepetalactone was determined to be 1550 mg/kg (about the same as aspirin), meaning you would have to force feed your average 5 kg cat ~8 grams in order to cause it any harm. So as long as you are reasonable with the extract it should pose no harm.

Still. That stuffs not going on or in any of my kitties directly.

The first think I thought of was that you should spray it on the tip of their tails.

It would probably create a perpetuum mobile or something.
Ex-Soviet Bloc Sexual Attack Swede of Tomorrow™
e-prime disclaimer: let it seem fairly unclear I understand the apparent subjectivity of the above statements. maybe.

INFORMATION SO POWERFUL, YOU ACTUALLY NEED LESS.

Bebek Sincap Ratatosk

The only conclusion I've come to on the topic of drugs is that none of the stereotypes and firm conclusions are true.. in much of a sense at all.

RWHN sees people that escape their problems through abuse. Thus in some sense he can claim that drugs are bad. Yet, most people that I know who smoke pot have jobs, families, run successful businesses, don't whinge on about 4:20 or The Man or anything else like that.

At the same time, I have had experiences with drugs that have entirely changed my outlook on life and much for the better IMO. Could it have happened without the drugs? Maybe. Would it have? Probably not. I doubt I would have ever put any stock in trying meditation (cause its from Satan, you know) if I hadn't experimented with LSD and shrooms and realized a hell of a lot about perception which I didn't grasp before. I didn't even know what I didn't know.

People that live their life being 100% for drugs are sadly confused. People that live their life being 100% against drugs are sadly confused.

Also, Nobody sprays Ketamine on their pot. That's just insane.
- I don't see race. I just see cars going around in a circle.

"Back in my day, crazy meant something. Now everyone is crazy" - Charlie Manson

Bebek Sincap Ratatosk

Quote from: Horrendous Foreign Liam Stoat on February 22, 2010, 02:43:36 PM
QuoteAlso, Nobody sprays Ketamine on their pot. That's just insane.

I've seen it done once or twice as a joke. Not to weigh it up more, as a 'fecking joke. English people have a funny sense of humour Rat.



Ok, let me rephrase... Nobody puts K on pot as part of the growing/drying or selling process, unless they're a crazy British person having one over on their friends...
- I don't see race. I just see cars going around in a circle.

"Back in my day, crazy meant something. Now everyone is crazy" - Charlie Manson

Bebek Sincap Ratatosk

Quote from: Horrendous Foreign Liam Stoat on February 22, 2010, 03:10:21 PM
oh it was not anyone they even knew.  :x and that pot was off to be redistributed and probably sold by the 1/8 also. . . horror. no mirth.

As a joke? K is not cheap and its not gonna up the value of their weed... so you're sure that this happened? I mean, I'm just saying it sounds far more like the scare stories that make no sense. However, I don't doubt that stupid monkeys may well do something stupid... seems that one would make a lot more money selling K and Pot rather than K laced pot...
- I don't see race. I just see cars going around in a circle.

"Back in my day, crazy meant something. Now everyone is crazy" - Charlie Manson