Author Topic: Open Bar: Free Russian Orphans with Every Purchase  (Read 75202 times)

PoFP

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #885 on: April 17, 2018, 05:21:16 pm »
Friend of a friend was in some PTSD study that involved MDMA.

I had never considered that one, but it does also appear to have Sigma Receptor activity. Specifically, it appears to over-activate Sigma-1 Receptors at recreational doses (In that reversing this action seems to decrease the drug's side effects), meaning it would likely activate them at realistic levels at the therapeutic (lower) dose. I'm definitely thinking some sort of interplay between Sigma-1 receptor agonism and increases in monoamine transmission (Dopamine, Serotonin, etc.) are the main causes for the therapeutic effects of these drugs at this point. I suspect a combination of Dextromethorphan and small amounts of Hyperforin (Found in St. John's Wart) might be adequate OTC treatments for both PTSD and Depression. Only small amounts of the Hyperforin would be recommended, as too much Serotonin transmission causes Serotonin Syndrome.

Hopefully the MDMA and Ketamine trials work out as well, as they would likely be stronger treatments when combined with the usual therapy.
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Doktor Howl

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #886 on: April 18, 2018, 12:58:01 am »
So I honked and gave a thumbs up to several groups of pro-education protestors on the way home from work.

Then it occurred to me to ask "what kind of society needs to protest in favor of education?"
Well, that's hardly my fault.  I was just doing what I do, doing my little dance, singing my little song, you know?  And then Hirley0 got on the dance floor and said

SHAKE THAT
First ^  Then V

And I did.  I didn't feel like I had any choice.  Between P-Funk and Hirley0, I became the man reptillian menace I am today.

Bootsy Collins did this to me.

Emo Howard

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #887 on: April 18, 2018, 07:37:39 am »
A third world country that is one by choice?

Frontside Back

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #888 on: April 18, 2018, 01:00:58 pm »
In a far away country my physical body happens to reside in, the media has been attacking a certain celebrity for their methamphetamine (read: pervitin) use for weeks now. Bringing such a topic to a public discourse gets my cockroach-senses tingling. How long do I have to flee the country?
sqos dnd ou os 'snq ooz uo punos ou

Cain

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #889 on: April 18, 2018, 01:04:20 pm »
If it's the country I'm thinking of, you should point out to your co-nationalists that an awful lot of Soviets were killed by dudes on pervitin.  Taking it is practically patriotic.

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #890 on: April 18, 2018, 06:47:14 pm »
Nationalism on meth, what could possibly go wrong  :lulz:

And with all the hippies upgrading their toy drugs, they'd have lot more people to lure into the carnage.
sqos dnd ou os 'snq ooz uo punos ou

LuciferX

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #891 on: April 19, 2018, 02:04:28 am »
Your Honor, defense proffers that the District Attorney presents itself as the "Doctor of convenience" in evidence for discovery thereof.
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Doktor Howl

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #892 on: April 19, 2018, 02:57:04 am »
Well, that's hardly my fault.  I was just doing what I do, doing my little dance, singing my little song, you know?  And then Hirley0 got on the dance floor and said

SHAKE THAT
First ^  Then V

And I did.  I didn't feel like I had any choice.  Between P-Funk and Hirley0, I became the man reptillian menace I am today.

Bootsy Collins did this to me.

Cain

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #893 on: April 19, 2018, 02:09:43 pm »
Speaking of Nazis, check out this diary https://imgur.com/a/22mHD

In the space of 2 months, Hoffman goes from "we will crush the untermenschen Russians" to "we will be lucky to get out alive".  There's also bonus whining about Russia's "gangster methods".

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #894 on: April 20, 2018, 12:51:54 am »
Speaking of Nazis, check out this diary https://imgur.com/a/22mHD

In the space of 2 months, Hoffman goes from "we will crush the untermenschen Russians" to "we will be lucky to get out alive".  There's also bonus whining about Russia's "gangster methods".


This should be printed everywhere, because everyone seems to have forgotten how this always ends.
Well, that's hardly my fault.  I was just doing what I do, doing my little dance, singing my little song, you know?  And then Hirley0 got on the dance floor and said

SHAKE THAT
First ^  Then V

And I did.  I didn't feel like I had any choice.  Between P-Funk and Hirley0, I became the man reptillian menace I am today.

Bootsy Collins did this to me.

Doktor Howl

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #895 on: April 21, 2018, 05:25:54 am »
So, I'm writing again.

I have decided to try something that is both optimistic and horrifying.  1st chapter up on Monday evening.
Well, that's hardly my fault.  I was just doing what I do, doing my little dance, singing my little song, you know?  And then Hirley0 got on the dance floor and said

SHAKE THAT
First ^  Then V

And I did.  I didn't feel like I had any choice.  Between P-Funk and Hirley0, I became the man reptillian menace I am today.

Bootsy Collins did this to me.

The Wizard Joseph

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #896 on: April 21, 2018, 05:42:01 pm »
So, I'm writing again.

I have decided to try something that is both optimistic and horrifying.  1st chapter up on Monday evening.

Yay!  :banana:
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hirley0

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #897 on: April 21, 2018, 07:01:09 pm »



Your Honor, defense proffers that the District Attorney presents itself as the "Doctor of convenience" in evidence for discovery thereof.

Cain

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #898 on: April 21, 2018, 10:47:11 pm »
So, it turns out the penalty for breaking and entering into someone's flat is...a written warning.

At least it is apparently the case...I don't know because no-one has actually officially told me.  I had to rely on my co-worker to pass on the gossip.

LuciferX

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Re: Open Bar: Free Russian Orphans with Every Purchase
« Reply #899 on: April 22, 2018, 11:14:28 am »
Hic Salta?
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